UNAIR NEWS –聽Staphylococcus aureus聽in Greek means a bunch of grapes.聽This bacterium was first discovered by a surgeon, Sir Alexander Ogston, in 1880. In 1884, Rosenbach was able to isolate a yellow bacterial colony from an abscess which was later given the name聽Staphylococcus aureus, aureus derived from the Latin meaning gold.
Staphylococcus aureus聽is the type of bacteria most often mentioned in the pathogenesis of atopic dermatitis (DA) and the improvement was first described in the 1970s.聽With this background, dr.聽Iskandar Zulkarnain Sp.KK (K) together with his colleagues conducted a study related to reducing the colonization of聽聽Staphylococcus aureus聽with vitamin D.
“The research that I did with the team was experimental analytic research.聽The aim was to evaluate the effect of oral vitamin D3 compared with placebo syrup to decrease Staphylococcus aureus听肠辞濒辞苍颈别蝉听,聽“explained the lecturer of Faculty of Medicine (FK).
From the genus聽Staphylococcus聽, he added, the bacterium聽Staphylococcus aureus聽is the most virulent and pathogenic species on the skin because it can affect the body’s condition through various methods both directly and indirectly.聽This bacterium is in the DA predilection area, namely antecubital and popliteal fossa as a moist area.
The lecturer who was born in Gadang, 64 years ago further explained, DA patients have lower vitamin D levels compared to non DA patients. Vitamin D can affect the immune mechanism through its immunomodulatory properties in innate and adaptive immunity.
“Vitamin D increases the production of antimicrobial peptides, especially cathelicidin. With a great urgency, research on the provision of vitamin D in Indonesia is still very limited, “he said.
The study sample used was all children patients with DA who met the criteria for acceptance of the sample, who came to Outpatient Unit of Dermatology and Venereology, Pediatric Dermatology Division Dr. Soetomo Hospital Surabaya. The research used consecutive techniques, conducted within 6 months.
“This research has been approved by the Ethics Committee of RSUD Dr.聽Soetomo Surabaya.聽All study subjects had signed informed consent (pediatric patients were represented by parents).聽The research showed that vitamin D3 can reduce聽Staphylococcus aureus聽colonization聽聽聽in DA patients.聽Morover, there is a significant difference in the percentage of decrease in聽Staphylococcus aureus聽colonization聽in the vitamin D3 group compared with the placebo, ” he stated.
Author: Dian Putri Apriliani
Editor: Nuri Hermawan
Details of the research available at:
Zulkarnain I.1, Rahmawati Y.W.1, Setyaningrum T.1, Citrashanty I.1, Aditama L.2, Avanti C.2. 2019. Vitamin D3 supplementation reduced聽Staphylococcus aureus聽co颅lonization in the skin of pediatric patients with atopic dermatitis.
