UNAIR NEWS –聽“Potential Teratogenic Exposure to Avoid Birth Defects in Animals” was the title of the inaugural speech of FKH UNAIR new professor, Prof.聽Dr.聽H. Bambang Poernomo Soenardirahardjo, Drh., Ms. Pa Vet.聽(K).聽He was confirmed as a professor of Veterinary Embryology from the Faculty of Veterinary Medicine on Thursday (14/12) at Garuda Mukti Hall, Campus C Management Office, UNAIR.
The professor of Embryology started his scientific oration by giving an elaboration of embryology that includes the development of normal embryos.聽For him, it was necessary to make it easier to understand the various studies on principles and descriptions related to the effects of teratogenic exposure.
“Therefore, to understand the mechanism of teratogen, we must first know the development of embryo since gametes encounter,” he explained.
About the development of embryo, Prof.聽Bambang also explained that the development is characterized by the development of blastosul which occurs in blastula phase.聽Blastosul, for him, serves as a bearing for embryonic development.聽However, in every phase of embryonic development, according to Prof.聽Bambang, there is a degree of susceptibility to different teratogens.
鈥淭he most sensitive period to cause birth defects in animals or livestock is during pregnancy from week three to week eighth,鈥 he added.
Furthermore, to minimize the defective birth with teratogenesis exposure, Prof.聽Bambang explained how teratogens work.聽According to him, the mechanism of teratogen is divided into three, teratogenic work mechanisms in the maternal body, teratogenic work in the placenta, and teratogenic work in embryonic bodies.
“However, the diverse nature of teratogenic chemicals involves several specific mechanisms,” he said.
At the end of the oration, Prof.聽Bambang described the death of the embryo.聽According to him, the death of the embryo is defined as the mortality of ovum and embryo fertility until the end of implantation.聽More or less, he added, there are 25-40 percent of cases of premature embryonic deaths that occur in farms.聽Death is more common in the early period of the embryo than the final period.
“Early embryonic death is considered an unhealthy genotype elimination process in every generation or because of double pregnancy in cattle and sheep,” he concluded.聽(*)
Author: Nuri Hermawan
Editor: Feri Fenoria
