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National level achievement, three Faculty of Veterinary Medicine students propose idea for Covid-19 antiviral candidates

UNAIR NEWS – The聽COVID-19 pandemic did not stop three students of Faculty of Veterinary Medicine (FKH) 东京热 (UNAIR) to make achievement at national level.聽Suwaibatul Annisa (class of 2017) with two of her friends Diva Salsabilla (class of 2017) and Ratna Wahyuning Prastiwi (class of 2017) managed to get 2nd place in 2020 Public Health National Competition (PHNC) held by the Research and Achievement Department of Student Executive Board (BEM), Faculty of Public Health UNAIR.聽

When confirmed by the聽UNAIR NEWS听迟别补尘,聽Suwaibatul Annisa explained that their wish to take part in the national competition was to convey their group’s ideas.聽She also wanted to show that veterinary medicine students have a broad field of science.

“Actually, studying at FKH is not only about animals, but can also be beneficial for human health,” she said.

After going through the paper selection, the FKH UNAIR team together with nine other teams from UI, UNDIP, UGM, ITB, UII, UB, ITS, and UPI presented their works on Saturday, October 10, 2020.聽In 2020 PHNC presentation, Suwaibatul Annisa or Ica and her team proposed an idea, “In Silico Screening聽of bioactive compounds in Indonesian herbal plants as antiviral candidates for Covid-19”.

“This idea is important for us especially at a critical time like now.聽The cure for COVID-19 has not been yet found.聽Besides, the biodiversity in Indonesia is also extraordinary,鈥 said Ica to聽UNAIR NEWS聽on Tuesday, October 13, 2020.

She added, in silico screening聽with聽molecular docking聽was chosen as the main method because it was considered effective in matching proteins and ligands before being tested聽in vitro聽or聽in vivo聽in order to find a drug that could cure COVID-19.聽Ica and the team tried to conduct聽screening聽in聽silico聽bioactive components of 6 herbs Indonesia, Abrus precatorius,聽Euphorbia tirucall,聽Sonchus arvensis,聽Calophyllum sp.,聽Glochidion sp.聽and聽Clerodendrum minahassae against the 3CL聽pro聽protein receptor聽(聽main protease聽SARS-COV-2) using a聽molecular docking聽method聽to determine the energy of the bond between the formed ligand-receptor complexes.

“We hope is that this idea can be followed up so the potential of Indonesian herbal plants can be explored, especially to 鈥榗onquer鈥 the pandemic, considering that until now the COVID-19 medicine has not been found,” she concluded. (*)

Author: Muhammad Suryadiningrat

Editor: Nuri Hermawan

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